The article describes a study of tolerance of uncertainty as the most important mechanism for the
effective functioning of a person in everyday, educational and professional activities. It presents data
on the manifestation of tolerance/ intolerance of uncertainty, motivation for success, perception of
the world, and anxiety among male and female students of higher educational institutions of Kazan
together with the relationship between these psychological parameters. The study aims to identify
the severity and interrelationships between tolerance for these factors. The study found psychological
differences between male and female students in terms of anxiety, motivation to achieve success,
and conviction in the kindness of the World, and indicated that in the males and females there is a
prevailing intolerance of uncertainty. The sources of this intolerance are shown. It also showed the
interrelations of intolerance of uncertainty with the motivation to achieve success among males. In
contrast, in female subjects, the motivation to achieve success is directly related to the peculiarities
of the world perception. At the same time, anxiety among students of both groups studied remained
low. A slight excess in the level of anxiety among female students is accompanied by a decrease in
the level of self-worth. The results of this study can be used to develop a theoretical model of personal
prerequisites for self-regulation of educational activities, training programs, and psychological
counselling.